SOS: Save our Science - Last minute Christmas

Now that Christmas is drawing to a close our thoughts turn exuberantly towards the January sales. Blowing all of our new gift vouchers and our remaining money on last minute impulse buys. The good news for all of us is that we may be able to blame these rash choices on our genes.

Impulsivity is described as doing something without foresight, and understanding it has major implications for a range of psychiatric disorders as well as explaining what will be going on in the high street over the next few weeks. Impulsive behaviour is very complex and under the control of many genes. It has many aspects, most especially reduced inhibitions, but also including reduced attention span, limited awareness of consequences and inappropriate responses to rewards. Impulsive behaviour is also known to be inherited in some cases. This new study shows that it is possible to identify the genes involved in this behaviour.

tMoL: Nucleus

The brain of the cell. It is one of the most well known elements of an animal cell, and is common to all higher organisms (eukaryotes – animals, plants,fungi), as with most structures inside a cell it does not occur in bacteria (prokaryotes). Most DNA in a cell is found in the nucleus, it is the storage centre for all of the information to make more cells. The nucleus is also full of proteins which control which genes are active in a cell and help to pack all of the DNA into such a tiny space. This is how cells are able to become specialised to a specific function, by controlling which genes are active.

Lab 1: Only the Nose Glows (The reality)

I’m back home for Christmas and all done with my first rotation. I’m going to start writing it all up tomorrow, 7000 words in 4 weeks. So it seemed like a good time to write a post about what I’ve actually been doing over the last 9 weeks.

I’ve been trying to find out what makes olfactory ensheathing cells (OECs) from neural crest stem cells (NCCs). This means I’ve been looking at which genes are active in these cells at different points in development. The information from an active gene is converted into a messenger molecule (mRNA) and this information is then used to construct a protein, which has a specific role within a cell. mRNA and proteins can be coloured using specific markers.

SOS: Save our Science - Save our Salmon

This is a story that's been going for a long while. The concerns over the effects of fish farming on wild fish populations. Also it's nice to take the science outside for a change. This new research is quite interesting and was well reported. Although the actual findings still need a lot of work.

A sudden population crash in wild salmon during 2002 caused mass panic for the authorities in Canada. This coincided with closer monitoring of farmed salmon, and resulted in the blame being placed on parasites transferred from farmed fish. The phenomenon has drawn the attention of many researchers and a new study appears to show that although there is transfer of parasitic sea lice between farmed and wild salmon it cannot be responsible for the decline in population.

SOS: Save our Science - Inside Endometriosis

I wrote this after reading the BBC article about the same paper. The work was very poorly explained, and the findings were completely mistranslated. However, this time the original paper was pretty good, although filled with statistics (Bleh!)

All women hate periods, but a small percentage have it much worse than others. They suffer from endometriosis; severe pains and poor fertility throughout their reproductive life. The illness is often passed down through families, so must be partially dependent on genes. A new study has identified where some of these genes may occur.

tMoL: The Meanings of Life - Boxes, little boxes

I’m creating this section as a means for me to blog without having to put in too much effort. In each post I’m going to pick one of the many words and acronyms developed by academics to confuse everyone else, and explain it for everyone to understand, and provide you with a few useful little facts. The first few are going to be pretty easy, words that come up in the media all the time. Words that everyone has heard and probably knows the meaning of but not necessarily some of the more interesting bits.

Cell – I want to start with cells because they are an important part of my work, they are generally most active and undergo the most changes during development. They are also the basis for life and are generally the start point of most discussions of the evolution of life (although actually there was a lot of good stuff before that, which tends to get overlooked). Also I will be talking about them to local school children in a few months and hopefully this will help me to organise some of my ideas.

This time it's personal - A quick look at life beyond labbing (including pictures of DNA cake)

This has been sat on my computer since Friday and I've been meaning it post it, but got distracted by other things. It seems appropriate to post it now as I had quite a non-worky day, I had loads of end of term things to finish off, and managed to catch up with old friends both at lunch and at dinner.

Also, if anyone hasn't seen it, I wrote a post for the Lab Rat a few days ago. 

Last night was the lab Christmas dinner, so I thought I’d follow it up with a piece on the social side of my life. It is true that biological research can be quite demanding in terms of time. Sometimes you just have to be in the lab late night, early morning or at the weekends, to make sure the animals or cells you are working with stay healthy and to collect data. Thus it is very important to balance this with a healthy social life, something I have not always be great at.